Carthage, MO – Stratum Nutrition®, an ingredient manufacturer and supplier in the nutraceutical industry, is proud to announce the publication of the 16th scientific study on NEM® brand eggshell membrane. This milestone further underscores the efficacy and safety of NEM® as a premier ingredient for joint health.

The latest study, published in the International Journal of Physical Medicine & Rehabilitation, was designed to evaluate whether NEM® brand eggshell membrane would reduce cartilage turnover or alleviate joint pain or stiffness, some of the major barriers to participation, either directly following exercise or 12 hours post-exercise, in healthy men and women versus placebo. Eighty-five healthy, men and women, aged 40-72, were randomly assigned to receive either oral NEM® or placebo once daily for two weeks while performing an exercise regimen on alternating days.

Key Findings of the Study:

• Supplementation with NEM® produced a significant absolute treatment effect (TEabs) versus placebo after both one week and two weeks of exercise for the primary endpoint, CTX-II.
• Rapid treatment responses were observed for both immediate pain and stiffness with results occurring as early as Day 1 and Day 5, respectively.
• A substantial chondroprotective effect was demonstrated from supplementation with NEM® through a lasting decrease in the cartilage degradation biomarker CTX-II.

"We are pleased that our follow-up healthy population clinical trial has recently been published. This is now the 16th published study investigating the incredible joint health benefits of NEM® and this study confirms the cartilage-sparing effect of NEM® in healthy exercising individuals," said Kevin Ruff, Ph.D., Sr. Director of Scientific Reseach at Stratum Nutrition®.

"We are pleased with the findings of this study, which reinforces NEM® as highly effective support for joint health," said Micah Osborne, President & CEO at Stratum Nutrition®. "The consistent results across multiple studies highlight our commitment to delivering science-backed ingredients that can truly make a difference in people's lives."

NEM® eggshell membrane is derived from the inner membrane of chicken eggshells, a natural source of key nutrients like collagen, glucosamine, chondroitin, and hyaluronic acid. These compounds work synergistically to support joint health, making NEM® an ideal choice for dietary supplements aimed at promoting joint support and mobility.

The extensive research on NEM® highlights its position as a leader in the joint health category, providing formulators and consumers alike with a trusted, scientifically validated ingredient. Stratum Nutrition® remains dedicated to advancing the science of nutrition and continues to invest in rigorous research to validate the benefits of its ingredients.

About Stratum Nutrition®:

Stratum Nutrition®, a business of ESM Technologies, LLC, is a trusted ingredient innovator and supplier to product formulators for human and pet health. Stratum offers a portfolio of research-supported ingredients and technology that stand out in their respective health categories as being progressive, safe, and effective, including NEM® brand eggshell membrane, Eggshell Membrane Collagen Support Complex, Bimuno® GOS prebiotic, LBiome™ Lactobacillus LB postbiotic, Ahiflower®, Stratum Sage Extract, VitaSperse® ingredient delivery technology, NatAxtin™ astaxanthin, Curcumin 95, CurQ+®, and ESC® brand eggshell calcium. These trusted ingredients are relied upon by consumers internationally.